The cute and comical Atelier series takes on a more serious tone in Atlier Ayesha. The game takes place in an era where Alchemy is coming to an end. Ayesha, an orphan girl sets off to search for her missing sister after her grand father dies. In her adventures, Ayesha can find several spots where she can synthesize items. The player can decide on a spot as her main base. Pay extra attention to the item synthesis process. A different item can emerge even when you use the same ingredients. The cauldron and the order at which you add ingredients play a huge part. In this game, 2D drawing and the 3D models merge even closer together, giving gamers an anime experience during the event scenes.